Case Fatality Ratio (CFR) for most common diseases

Case Fatality Ratio (CFR) for most common diseases

Probability of dying as a result of a given disease. Is a result of a mixture of disease severity and quality of health care.

Numerator: 
Total number of fatalities related to the disease in a defined administrative or health area in a given time period
Denominator: 
Total number of cases related to the disease in the same administrative or health area and the same time period
Disaggregation: 
Administrative area; health area; sex
Threshold / Standard: 
Cholera : 1 per cent or lower; Shigella dysentery : 1 per cent or lower; typhoid : 1 per cent or lower; meningococcal meningitis : varies, 5-15 per cent; malaria : varies, aim for <5 per cent in severely ill malaria patients; measles : varies, 2-21 per cent reported in conflict-affected settings, aim for <5 per cent. Follow-up of trends
General guidance: 
Interpretation: the CFR is an indicator of the quality of case management, late arrival at the facility or severity of disease. Limitations: most likely to be biased upwards because only more severe cases normally go to clinics.
Guidance on phases: 
There is a differing level of quality of data which can be collected at different phases of the emergency depending on the context, eg the data available and the systems for data collection in place before the crisis, the accessibility of the affected areas, the resources on the ground, etc...
Phase applicability: 
Pre-crisis/Baseline
Phase 1
Phase 2
Phase 3
Phase 4
Data Sources: 
Numerator: health facility based surveillance; routine health facility reporting system Denominator: health facility based surveillance; routine health facility reporting system
Comments: 
Further guidance: IDSR guide CDC Afro. NB: This indicator is relevant to WASH only for certain diseases. (http://www.cdc.gov/globalhealth/dphswd/idsr/pdf/Technical%20Guidelines/IDSR%20Technical%20Guidelines%202nd%20Edition_2010_English.pdf)
Code: 
H-R.3
Sub-domain: 
H3 Communicable diseases
H5 Non communicable diseases and mental health
Unit of Measurement: 
Individual
Key indicator: 
Yes
Types: 
Baseline
Indicator used for response monitoring ?: 
Yes
Standards: 
Sphere: Essential health services – control of communicable diseases standard 3: Outbreak detection and response (Key indicator 4)
Global Clusters: 
Health
Sector cross-tagging: 
N1 Prevention and Management of Acute Malnutrition
N2 Infant and Young Child Feeding
N3 Prevention and Control of Micronutrients Deficiencies
(R) Early Recovery
S1 Shelter
S2 Shelter-related NFI
W7 Aggravating Factors